PAÜ .:. Eğitim Öğretim Bilgi Sistemi

COURSE INFORMATION

Course Code	Course Title	L+P Hour	Semester	ECTS
TBI 610	MOLECULAR BIOLOGY OF CANCER	2 + 2	2nd Semester	5

COURSE DESCRIPTION

Course Level	Doctorate Degree
Course Type	Elective
Course Objective	The aim of the lecture to understand knowledge of the molecular mechanisms of cancer At the end of this lecture, students are expected to have knowledge of cell cycle and its regulation, molecular mechanisms of carsinogenesis, morphological characteristics of cancer cells at PhD level and competence to analyze the knowledge at research area .
Course Content	Cell cycle, celular diferantiation, apoptosis, cell cycle phase check points and regulation, tumorigenesis, oncogenes and tumor supressor genes, protooncogenes and oncogenes, How does oncogenes activation in cancer biology Classification of oncogenes: growth factors, tyrosine kinase receptors, nonreceptors tyrosine kineases, ser/thr kinases, nuclear transcription factors, DNA repair mechanisms and cancer, chemical carcinogens and mutations, marker chromosomes for specific cancer type, chromoseome translocation and cancer. .
Prerequisites	No the prerequisite of lesson.
Corequisite	No the corequisite of lesson.
Mode of Delivery	Face to Face

COURSE LEARNING OUTCOMES

1	Explain the control mechanisms of cell cycle, and how a normal cell is transforme into a cancer cell at high-level
2	Define onkogenes, tumor supressor geens, invasion and metastasis

COURSE'S CONTRIBUTION TO PROGRAM

	PO 01	PO 02	PO 03	PO 04	PO 05	PO 06	PO 07	PO 08	PO 09	PO 10	PO 11	PO 12
LO 001	5	5	3	4	4	5	4	3	3	3	3	4
LO 002	5	5	3	4	4	5	4	3	3	3	3	4
Sub Total	10	10	6	8	8	10	8	6	6	6	6	8
Contribution	5	5	3	4	4	5	4	3	3	3	3	4

ECTS ALLOCATED BASED ON STUDENT WORKLOAD BY THE COURSE DESCRIPTION

Activities	Quantity	Duration (Hour)	Total Work Load (Hour)
Course Duration (14 weeks/theoric+practical)	14	2	28
Hours for off-the-classroom study (Pre-study, practice)	14	2	28
Mid-terms	1	30	30
Final examination	1	44	44
Total Work Load ECTS Credit of the Course			130 5

COURSE DETAILS

Select Year

Course Details

Course Code	Course Title	L+P Hour	Course Code	Language Of Instruction	Course Semester
TBI 610	MOLECULAR BIOLOGY OF CANCER	2 + 2	1	Turkish	2023-2024 Fall

Course Coordinator	E-Mail	Phone Number	Course Location	Attendance
Prof. Dr. İBRAHİM AÇIKBAŞ	iacikbas@pau.edu.tr		KKM A0318	%80

Goals		The aim of the lecture to understand knowledge of the molecular mechanisms of cancer At the end of this lecture, students are expected to have knowledge of cell cycle and its regulation, molecular mechanisms of carsinogenesis, morphological characteristics of cancer cells at PhD level and competence to analyze the knowledge at research area .
Content		Cell cycle, celular diferantiation, apoptosis, cell cycle phase check points and regulation, tumorigenesis, oncogenes and tumor supressor genes, protooncogenes and oncogenes, How does oncogenes activation in cancer biology Classification of oncogenes: growth factors, tyrosine kinase receptors, nonreceptors tyrosine kineases, ser/thr kinases, nuclear transcription factors, DNA repair mechanisms and cancer, chemical carcinogens and mutations, marker chromosomes for specific cancer type, chromoseome translocation and cancer. .

Topics

Materials

Materials are not specified.

Resources

Course Assessment

Assesment Methods	Percentage (%)	Assesment Methods Title
Final Exam	50	Final Exam
Midterm Exam	50	Midterm Exam

L+P: Lecture and Practice
PQ: Program Learning Outcomes
LO: Course Learning Outcomes

Prospective Student