1. FIRST CYCLE - BACHELOR'S DEGREE
  2. FACULTY OF DENTISTRY
  3. DENTISTRY DEPARTMENT
  4. 279 DENTISTRY
Course Information Course Learning Outcomes Course's Contribution To Program ECTS Workload Course Details
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COURSE INFORMATION
Course CodeCourse TitleL+P HourSemesterECTS
DHF 2903MEDICAL BIOLOGY AND GENETICS2 + 11st Semester6

COURSE DESCRIPTION
Course Level Bachelor's Degree
Course Type Compulsory
Course Objective Explain the importance and use of molecular genetics in todays medicine. Assess and understand papers written in the field of molecular genetics. Discuss the methodology of papers written in the field of molecular genetics and state alternative applicable approaches to the given methodology. Identify the development, structure and function of cell and its subcomponents. Evaluate the biochemical process of the cell. Clarify how significant molecular biology and how we can utilize molecular biology. Explain what the human molecular biology is based on. Explain how genes are organized in prokaryote, eukaryotes and function of regulatory elements. Explain how constitutive and inducible gene expression achieved in organisms. Express chromosomes harboring genes causing pathology in human. Distingiush genetic disease caused by monogenic disorders and multifactorial disorders. Clarify all genetic disorders in man with respective mechanisms, chromosomal basis of genetic disorders. Express chromosomal basis of genetic disorders such as diseases caused by anoploidies and mechanism of inheritance and maternal inheritance.
Course Content The Origin and Evolution of Cells; The Molecules of Cells; Cell Membranes; Cell Metabolism and Evolution of Metabolism; Fundamentals of Molecular Biology: Heredity, Genes and DNA, Expression of Genetic Information, Recombinant DNA, Detection of Nucleic Acids and Proteins, Gene Function in Eukaryotes; The Complexity of Eukaryotic Genomes; Chromosomes and Chromatin; The Sequences of Complete Genomes; DNA Replication; DNA Repair; Recombination between Homologous DNA Sequences, DNA Rearrangements; Transcription in Prokaryotes; Regulation of Transcription in Eukaryotes, RNA Processing; Translation of mRNA, Protein Folding and Processing, Regulation of Protein Function, Protein Degradation. Nucleus, The Nuclear Envelope and Traffic between the Nucleus and the Cytoplasm, The Nucleolus and rRNA Processing; Protein Sorting and Transport: The Endoplasmic Reticulum, Golgi Apparatus, and Lysosomes; Mitochondria, The Mechanism of Oxidative Phosphorylation, Peroxisomes; The Cytoskeleton and Cell Movement; Cell Cycle and Cell Divisions (Mitosis and Meiosis); Fundamentals of Genetics: Terminology,Mendel’s Laws, Mendelian Genetics; Relations of Genes (Deviations of Mendel’s Ratios); Non-Mendelian Heredity; Modes of Heredity; Chromosomal Aberrations in Man; Single Gene Diseases in Man.
Prerequisites No the prerequisite of lesson.
Corequisite No the corequisite of lesson.
Mode of Delivery Face to Face

COURSE LEARNING OUTCOMES
1To be able to define structure and functions of cell and its components; Ability to explain cell cycle, divisions and control mechanisms.
2The ability to explain the structure of chromosomes and chromosome-related diseases and to know about the causative agents and the ways of protection.

COURSE'S CONTRIBUTION TO PROGRAM
PO 01PO 02PO 03PO 04PO 05PO 06PO 07PO 08PO 09PO 10PO 11PO 12PO 13PO 14
LO 001              
LO 002              
Sub Total              
Contribution00000000000000

ECTS ALLOCATED BASED ON STUDENT WORKLOAD BY THE COURSE DESCRIPTION
ActivitiesQuantityDuration (Hour)Total Work Load (Hour)
Hours for off-the-classroom study (Pre-study, practice)32266
Final examination212
Midterm224
Course Duration32884
Total Work Load

ECTS Credit of the Course





156

6
COURSE DETAILS
 Select Year   


 Course TermNoInstructors
Details 2023-2024 Summer1İBRAHİM AÇIKBAŞ
Details 2023-2024 Summer1İBRAHİM AÇIKBAŞ
Details 2023-2024 Summer1İBRAHİM AÇIKBAŞ
Details 2023-2024 Summer1İBRAHİM AÇIKBAŞ
Details 2023-2024 Summer1İBRAHİM AÇIKBAŞ
Details 2023-2024 Summer1İBRAHİM AÇIKBAŞ
Details 2023-2024 Summer1İBRAHİM AÇIKBAŞ
Details 2022-2023 Summer1İBRAHİM AÇIKBAŞ
Details 2022-2023 Summer1İBRAHİM AÇIKBAŞ
Details 2022-2023 Summer1İBRAHİM AÇIKBAŞ
Details 2022-2023 Summer1İBRAHİM AÇIKBAŞ
Details 2022-2023 Summer1İBRAHİM AÇIKBAŞ
Details 2022-2023 Summer1İBRAHİM AÇIKBAŞ
Details 2022-2023 Summer1İBRAHİM AÇIKBAŞ
Details 2021-2022 Summer1İBRAHİM AÇIKBAŞ
Details 2021-2022 Summer1İBRAHİM AÇIKBAŞ
Details 2021-2022 Summer1İBRAHİM AÇIKBAŞ
Details 2021-2022 Summer1İBRAHİM AÇIKBAŞ
Details 2021-2022 Summer1İBRAHİM AÇIKBAŞ
Details 2021-2022 Summer1İBRAHİM AÇIKBAŞ
Details 2020-2021 Summer1İBRAHİM AÇIKBAŞ
Details 2020-2021 Summer1İBRAHİM AÇIKBAŞ
Details 2020-2021 Summer1İBRAHİM AÇIKBAŞ
Details 2020-2021 Summer1İBRAHİM AÇIKBAŞ
Details 2019-2020 Summer1İBRAHİM AÇIKBAŞ


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Course Details
Course Code Course Title L+P Hour Course Code Language Of Instruction Course Semester
DHF 2903 MEDICAL BIOLOGY AND GENETICS 2 + 1 1 Turkish 2023-2024 Summer
Course Coordinator  E-Mail  Phone Number  Course Location Attendance
Prof. Dr. İBRAHİM AÇIKBAŞ iacikbas@pau.edu.tr KKM A0007 %70
Goals Explain the importance and use of molecular genetics in todays medicine. Assess and understand papers written in the field of molecular genetics. Discuss the methodology of papers written in the field of molecular genetics and state alternative applicable approaches to the given methodology. Identify the development, structure and function of cell and its subcomponents. Evaluate the biochemical process of the cell. Clarify how significant molecular biology and how we can utilize molecular biology. Explain what the human molecular biology is based on. Explain how genes are organized in prokaryote, eukaryotes and function of regulatory elements. Explain how constitutive and inducible gene expression achieved in organisms. Express chromosomes harboring genes causing pathology in human. Distingiush genetic disease caused by monogenic disorders and multifactorial disorders. Clarify all genetic disorders in man with respective mechanisms, chromosomal basis of genetic disorders. Express chromosomal basis of genetic disorders such as diseases caused by anoploidies and mechanism of inheritance and maternal inheritance.
Content The Origin and Evolution of Cells; The Molecules of Cells; Cell Membranes; Cell Metabolism and Evolution of Metabolism; Fundamentals of Molecular Biology: Heredity, Genes and DNA, Expression of Genetic Information, Recombinant DNA, Detection of Nucleic Acids and Proteins, Gene Function in Eukaryotes; The Complexity of Eukaryotic Genomes; Chromosomes and Chromatin; The Sequences of Complete Genomes; DNA Replication; DNA Repair; Recombination between Homologous DNA Sequences, DNA Rearrangements; Transcription in Prokaryotes; Regulation of Transcription in Eukaryotes, RNA Processing; Translation of mRNA, Protein Folding and Processing, Regulation of Protein Function, Protein Degradation. Nucleus, The Nuclear Envelope and Traffic between the Nucleus and the Cytoplasm, The Nucleolus and rRNA Processing; Protein Sorting and Transport: The Endoplasmic Reticulum, Golgi Apparatus, and Lysosomes; Mitochondria, The Mechanism of Oxidative Phosphorylation, Peroxisomes; The Cytoskeleton and Cell Movement; Cell Cycle and Cell Divisions (Mitosis and Meiosis); Fundamentals of Genetics: Terminology,Mendel’s Laws, Mendelian Genetics; Relations of Genes (Deviations of Mendel’s Ratios); Non-Mendelian Heredity; Modes of Heredity; Chromosomal Aberrations in Man; Single Gene Diseases in Man.
Topics
WeeksTopics
1 Structure of cell
2 Function of the cells
3 Cell membrane and diffusions
4 DNA and RNA
5 Chromosomes and cytogenetics
6 Organisation of human genome
7 DNA replicaiton
8 Transcription and RNA processing
9 Translation
10 Midterm exam
11 Midterm exam
12 Mitosis and meiosis
13 Mendelian inheritance
14 Autosomal inheritance
15 Gender linked inheritance
16 Mutations and polymorphisms
17 Phenotype genotype relationship
18 DNA repair
19 DNA analysis
20 Prenatal diagnosis
21 Cancer
22 Genetic engineering
23 Gene therapy
24 Regenerative medicine
25 mitochondrion
26
27
28
Materials
Materials are not specified.
Resources
ResourcesResources Language
Ders sunumlarıTürkçe
Ders sunumlarıTürkçe
Hücre: Moleküler Yaklaşım, 3. baskı (Cooper & Hausman), Çeviri Ed., Sakızlı M, Atabey N, 2006. Türkçe
Genetik Kavramlar, 6. Baskı, Klug WS, Cummins MR, Çeviri Ed.: Cihan Öner, 2003, Palme Yayıncılık, Ankara. Türkçe
Ders sunumlarıTürkçe
Ders sunumlarıTürkçe
Hücre: Moleküler Yaklaşım, 3. baskı (Cooper & Hausman), Çeviri Ed., Sakızlı M, Atabey N, 2006. Türkçe
Genetik Kavramlar, 6. Baskı, Klug WS, Cummins MR, Çeviri Ed.: Cihan Öner, 2003, Palme Yayıncılık, Ankara. Türkçe
Course Assessment
Assesment MethodsPercentage (%)Assesment Methods Title
Final Exam60Final Exam
Midterm Exam20Midterm Exam 1
Midterm Exam20Midterm Exam 2
L+P: Lecture and Practice
PQ: Program Learning Outcomes
LO: Course Learning Outcomes