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COURSE INFORMATION
Course CodeCourse TitleL+P HourSemesterECTS
TBI 612SIGNALING MECHANISMS2 + 23rd Semester5

COURSE DESCRIPTION
Course Level Doctorate Degree
Course Type Elective
Course Objective The aim of the lecture to understand knowledge of major signaling pathways At the end of this lecture, students are expected to have knowledge of EGFR family and signaling different, TNF receptor family and signaling pathways, PI3K/AKT/NFkB pathway, and wnt pathways signaling mechanisms at PhD level and competence to analyze the knowledge at research area .
Course Content Cell Cycle Control The Biology of EGF Family Receptors TNF signaling The signaling of IFN receptors PI3K and AKT Pathways The role of NFkB in Cellular transformation, invasion and metastasis .
Prerequisites No the prerequisite of lesson.
Corequisite No the corequisite of lesson.
Mode of Delivery Face to Face

COURSE LEARNING OUTCOMES
1Define fundamental pathways in cell death
2Understand and discuss signal transduction pathways that involve in transforming a normal cell into a cancer cell
3Explain thegenes and signal transduction pathways that involve in apoptosis, invasion, and metastasis

COURSE'S CONTRIBUTION TO PROGRAM
PO 01PO 02PO 03PO 04PO 05PO 06PO 07PO 08PO 09PO 10PO 11PO 12
LO 001553445433334
LO 002553445433334
LO 003553445433334
Sub Total1515912121512999912
Contribution553445433334

ECTS ALLOCATED BASED ON STUDENT WORKLOAD BY THE COURSE DESCRIPTION
ActivitiesQuantityDuration (Hour)Total Work Load (Hour)
Course Duration (14 weeks/theoric+practical)14228
Hours for off-the-classroom study (Pre-study, practice)14228
Mid-terms13030
Final examination14444
Total Work Load

ECTS Credit of the Course






130

5
COURSE DETAILS
 Select Year   


 Course TermNoInstructors
Details 2023-2024 Spring1SELDA ŞİMŞEK
Details 2022-2023 Spring1SELDA ŞİMŞEK
Details 2021-2022 Spring1SELDA ŞİMŞEK
Details 2014-2015 Spring1HAKAN AKÇA
Details 2012-2013 Fall1HAKAN AKÇA
Details 2011-2012 Fall1HAKAN AKÇA
Details 2009-2010 Spring1HAKAN AKÇA


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Course Details
Course Code Course Title L+P Hour Course Code Language Of Instruction Course Semester
TBI 612 SIGNALING MECHANISMS 2 + 2 1 Turkish 2023-2024 Spring
Course Coordinator  E-Mail  Phone Number  Course Location Attendance
Assoc. Prof. Dr. SELDA ŞİMŞEK seldas@pau.edu.tr KKM A0307 KKM A0321 %80
Goals The aim of the lecture to understand knowledge of major signaling pathways At the end of this lecture, students are expected to have knowledge of EGFR family and signaling different, TNF receptor family and signaling pathways, PI3K/AKT/NFkB pathway, and wnt pathways signaling mechanisms at PhD level and competence to analyze the knowledge at research area .
Content Cell Cycle Control The Biology of EGF Family Receptors TNF signaling The signaling of IFN receptors PI3K and AKT Pathways The role of NFkB in Cellular transformation, invasion and metastasis .
Topics
WeeksTopics
1 EGFR pathway
2 EGFR pathway
3 TNF pathway
4 IFN pathway
5 PI3K pathway
6 exam
7 NfkB pathway
8 NfkB pathway
9 MAP pathway
10 Mat 1 pathway
11 invasion pathway
12 invasion pathway
13 metastaz pathway
14 metastaz pathway
Materials
Materials are not specified.
Resources
Course Assessment
Assesment MethodsPercentage (%)Assesment Methods Title
Final Exam50Final Exam
Midterm Exam50Midterm Exam
L+P: Lecture and Practice
PQ: Program Learning Outcomes
LO: Course Learning Outcomes